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Based on multiple MAPP studies, suggest that IC/BPS patients who have concurrent nonurological chronic pain conditions or widespread pain have a more systemic condition and may be more likely to experience symptom progression and decreased quality of life than those with bladder-focused symptoms

Another important study reported that Prx2 reacts with H 2 O 2 at a constant rate (1.3 10 7 M 1 s 1 ) comparable with that of CAT and GPx [75]

Self-reported community protocols commonly describe once-daily dosing with on/off cycling, motivated partly by the absence of any long-term human safety data and partly by a community perception of diminishing returns or tolerance over continued use

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Sanchez, L., Wang, Y., Siegel, D